The Rx Bricks Podcast
The Rx Bricks Podcast
Congenital Disorders of the Central Nervous System
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The central nervous system (CNS) comprising the brain and spinal cord is an incredibly complex part of the human body, so it is no surprise that sometimes things go awry during development. The various anatomic anomalies that result can be so severe as to be incompatible with life, such as when most or all of…

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The Rx Bricks Podcast
The Rx Bricks Podcast
Signs of Upper and Lower Motor Neuron Lesions
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Every movement we make is caused by the contraction of different muscles, which are themselves controlled by the neurons that innervate them. However, one long nerve fiber does not run from the brain all the way down the spinal cord to reach our muscles. Instead, our bodies use a two-neuron system. After listening to this…

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The Rx Bricks Podcast
The Rx Bricks Podcast
Brain Energy Metabolism
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For the most part, the brain relies on glucose as its main energy source. In fact, we say the brain preferentially uses glucose. In times of low glucose levels such as fasting or starvation, the brain can use ketones, lactate, and amino acids (worth noting: the brain does not use fatty acids to generate energy).…

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Development of the Nervous System
The Rx Bricks Podcast
The Rx Bricks Podcast
Development of the Nervous System
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Early in fetal development, the precursors of the major systems in the body are outlined. The three germ layers (endoderm, mesoderm, ectoderm) are formed during the third week of development. We’ll focus on the ectoderm, from which the entire nervous system (central and peripheral) forms. But first, let’s back up to review the anatomy of…

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Tension headaches
The Rx Bricks Podcast
The Rx Bricks Podcast
Migraine, Cluster, and Tension Headaches
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Headaches are an unavoidable fact of life and often are nothing more than the result of sitting through one too many lectures. However, they can become debilitating and get in the way of daily life, especially when they become recurrent. Although some headaches have symptoms other than head pain, we typically think of headache pain…

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Pain Mechanisms
The Rx Bricks Podcast
The Rx Bricks Podcast
Pain Mechanisms
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Pain is a sensation that warns of potential injury and alerts the person to avoid or treat it. For example, if you touch a hot object, you will feel pain and immediately remove your hand from that object, protecting your hand from further damage. As much as pain can burden and torment, ultimately it is…

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The Rx Bricks Podcast
The Rx Bricks Podcast
Neurodegenerative Diseases: Foundations and Framework
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Neurodegenerative diseases are a group of relatively common, progressive neurologic conditions that tend to affect people as they age. Basically, neurons in the brain die, causing functional losses. The part of the brain affected determines whether patients will experience dementia (deteriorated cognitive function), psychiatric disturbances, problems with movement, or a combination of these. These conditions…

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Synaptic Transmission
The Rx Bricks Podcast
The Rx Bricks Podcast
Synaptic Transmission
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In this AudioBrick, we are heading into neurology and the special senses by looking at synaptic transmission.  Synaptic transmission is the official term for how neurons communicate with each other across the junction between them, called the synapse. We’re going to break down that process into its components, beginning with the synapse. After listening, you…

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